WebThese highlights do not include all the information needed to use PLAVIX safely and effectively. See full prescribing information for PLAVIX. PLAVIX ® (clopidogrel bisulfate) tablets, for oral use Initial U.S. Approval: 1997 . WARNING: DIMINISHED ANTIPLATELET EFFECT IN PATIENTS WITH TWO LOSS -OF-FUNCTION ALLELES OF THE … WebClopidogrel Bisulfate API is metabolized to its active form by carboxylesterase-1 and the active metabolite of Clopidogrel selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet P2Y12 receptor and the subsequent ADP- mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation.
Clopidogrel: 7 things you should know - Drugs.com
WebMay 5, 2024 · Avoid concomitant use of clopidogrel bisulfate with omeprazole or esomeprazole because both significantly reduce the antiplatelet activity of clopidogrel bisulfate [see Drug Interactions ( 7.1)] . 5.2 General Risk of Bleeding. P2Y12 inhibitors (Thienopyridines), including clopidogrel bisulfate, increase the risk of bleeding. ... WebClopidogrel is used to prevent heart attack and stroke in people who are at high risk of these events, including those with a history of myocardial infarction and other forms of acute coronary syndrome, stroke, and those with peripheral artery disease . shoney\u0027s chattanooga breakfast hours
Side Effects of Plavix (Clopidogrel Bisulfate), Warnings, Uses - RxList
WebClopidogrel — sold under the brand name Plavix, among others — is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. It is also used together with aspirin in heart attacks … WebNov 28, 2024 · Clopidogrel bisulfate, USP is a white to off-white powder. It is practically insoluble in water at neutral pH but freely soluble at pH 1. It also dissolves freely in methanol, dissolves sparingly in methylene chloride, and is practically insoluble in ethyl ether. It has a specific optical rotation of about +56°. WebAug 4, 2024 · Plavix is a prescription drug used to reduce the risk of heart attack and stroke in adults who: * For this use, Plavix is taken with aspirin. The active ingredient in Plavix is clopidogrel. (An ... shoney\u0027s charleston west virginia