Phospho s727
WebProperties. Description. Rabbit Monoclonal Antibody to STAT3 (phospho S727) Background. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. WebPhospho-Stat3 (Ser727) Antibody recognizes endogenous levels of Stat3 only when phosphorylated at Ser727. The antibody does not significantly cross-react with the …
Phospho s727
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WebCitations: (293) The Phospho-Stat3 (Ser727) Antibody from Cell Signaling Technology is a Rabbit Polyclonal antibody to STAT3. This antibody recognizes Human, Mouse, and Rat antigen. The Phospho-Stat3 (Ser727) Antibody has been validated for the following applications: Precipitation, ChIP, Immunoprecipitation, and Western Blot. WebPhospho-Stat1 (Ser727) Antibody detects endogenous levels of Stat1α only when phosphorylated at Ser727. This site is deleted in Stat1β. This antibody does not …
WebHuman/Mouse Phospho-Stat 1 (S727) and Total Stat 1 ELISA RayBiotech The store will not work correctly in the case when cookies are disabled. JavaScript seems to be disabled in … WebHSP27 is phosphorylated at Ser15, Ser78, and Ser82 by MAPKAPK-2 as a result of the activation of the p38 MAP kinase pathway (2,3). Phosphorylation of HSP27 causes a …
WebJan 15, 2001 · S727 phosphorylation of STAT1 in interferon-γ (IFN-γ)-treated mouse fibroblasts occurred without a need for p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinases 1 and 2 or c-Jun kinases, and required both an intact SH2 domain and phosphorylation of Y701. WebHuman Phospho-STAT3 (S727) Antibody Summary Species Reactivity Human Specificity Detects human STAT3 when phosphorylated at S727 in Western blots. Source Polyclonal Rabbit IgG Purification Antigen Affinity-purified Immunogen Phosphopeptide containing human STAT3 S727 site Accession # P40763 Formulation
WebMay 4, 2024 · Serine kinases play a more nuanced role in regulating Stat3 due to direct Stat3 activation through S727 phosphorylation ( 16) by kinases such as mTOR ( 7) and others, which also have the potential for competing inhibitory effects from parallel downregulation of Stat3 tyrosine phosphorylation pathways ( 17 ).
WebDec 1, 2024 · LIF/pS727-STAT3-elicited MET followed by IL6/pY705-STAT3-elicited EMT regulated by BM-MSCs is required for CSC heterogeneity and cancer metastasis. These … ctr phase iiWebHere, we studied the role of STAT3 activation on tyrosine 705 (Y705) and serine 727 (S727) in glioma radioresistance. This study explored STAT3 phosphorylation on Y705 (pSTAT3-Y705) and S727 (pSTAT3-S727) in glioma cell lines and in clinical samples. Radiosensitizing effect of STAT3 activation down-modulation by Gö6976 was explored. ctrpf_meWebUsing a combination of HepG2-stat3-knockdown cells reconstituted with various STAT3 mutants and protein kinase inhibitors, we showed that phospho-S727 has an intrinsic … earthway spreader settings chartWebApr 23, 2002 · Phosphorylation of S727 in Stat1 can be induced by a variety of stimuli such as IFN-γ, lipopolysaccharide, and UV, and p38 mitogen-activated protein (MAP) kinase has been implicated in lipopolysaccharide- or UV-induced phosphorylation of S727 in Stat1 ( … earthway to scotts conversionWebWestern blot - Phospho-STAT3-S727 Rabbit pAb (AP0474) Western blot analysis of extracts of various cell lines, using Phospho-STAT3-S727 antibody (AP0474) at 1:1000 dilution.HepG2 cells and C6 cells were treated by PMA/TPA (200 nM) at 37℃ for 30 minutes after serum-starvation overnight.HepG2 cells were treated by CIP (20uL/400ul) at 37℃ for ... earthway spreader settings for fertilizerWebHuman/Mouse Phospho-Stat 1 (S727) and Total Stat 1 ELISA. Be the first to review this product . RayBio® Human/Mouse Phospho-Stat 1 (S727) and Total Stat 1 ELISA Kit. This assay semi-quantitatively measures phosphorylated Stat 1 (Ser727) and Total Stat 1 in lysate samples. MANUAL / SDS. As low as $567.00. Size earth wealth energyWebS727 phosphorylation is regulated directly by fibroblast growth factor/Erk signaling and crucial in the transition of mESCs from pluripotency to neuronal commitment. Loss of S727 phosphorylation resulted in significantly reduced neuronal differentiation potential, which could be recovered by a S727 phosphorylation mimic. ... ctrpixbet