WebDec 21, 2024 · Current cartilage restoration procedures are varied and include marrow stimulation techniques, osteochondral transplants, cellular-based repair, and synthetic or biological scaffolds. 1-3 Despite technological advancements in cartilage restoration procedures, many shortcomings exist, and many ultimately do not provide long-term benefit. WebMar 15, 2024 · An ideal scaffold for cartilage tissue engineering should meet some requirements includes biocompatibility, biodegradability, and sufficient mechanical …
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WebFeb 28, 2024 · Optimal mechanical properties of a scaffold for cartilage regeneration using finite element analysis Optimal mechanical properties of a scaffold for cartilage … WebThis cartilage mimicked the biofunctional and mechanical properties of an ear cartilage. These results indicate that autologous chondrocyte-seeded PGA scaffolds fabricated following our optimized procedure have immense potential as a solution for obtaining enough cartilage for auricular reconstruction and opens new avenues to redefine ... linda smith dundee university
Optimization of 3D autologous chondrocyte-seeded polyglycolic
WebDistinctive characteristics of articular cartilage such as avascularity and low chondrocyte conversion rate present numerous challenges for orthopedists. Tissue engineering is a novel approach that ameliorates the regeneration process by exploiting the potential of cells, biodegradable materials, and growth factors. However, problems exist with the use of … WebMay 6, 2024 · Cartilage Repair Using a Hyaluronic Acid-Based Scaffold With Bone Marrow Aspirate Compared With Microfracture for Focal Articular Cartilage Damage of the Hip (CHASE) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S ... WebSep 24, 2024 · Cartilage lesions can lead to progressive cartilage degeneration; moreover, they involve the subchondral bone, resulting in osteoarthritis (OA) onset and progression. Bioactive glasses, with the dual function of supporting both bone and cartilage regeneration, have become a promising biomaterial for cartilage/bone engineering applications. This is … hot flash night sweats